More than 22% of older adults hospitalized with respiratory syncytial virus (RSV) infection experience acute heart disease, according to a study published online April 15. JAMA Internal Medicine.

Rebecca C. Woodruff, MD, MPH, of the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues conducted a cross-sectional study examining surveillance data from the RSV Inpatient Surveillance Network. To estimate the weighted period prevalence of acute cardiac events, we examined RSV infection cases in adults 50 years and older within 12 states over 5 RSV seasons.

A total of 6,248 hospitalized adults with laboratory-confirmed RSV infection were included. The researchers found that the weighted estimated prevalence of experiencing a cardiac event was 22.4%; the weighted estimated prevalence of acute heart failure, acute ischemic heart disease, hypertensive crisis, ventricular tachycardia, and acute heart failure was 15.8%; We found that 7.5, 1.3, 1.1, and 0.6%. respectively cardiogenic shock.

The risk of experiencing an acute cardiac event was higher in adults with underlying cardiovascular disease (33.0 vs. 8.5%; adjusted risk ratio) [aRR], 3.51). Among adults hospitalized with RSV infection, 18.6% required admission to an intensive care unit (ICU) and 4.9% died. Those who experienced an acute cardiac event had a higher risk of ICU admission and in-hospital death (aRR, 1.54 and 1.77, respectively).

“Acute heart disease contributes significantly to the burden of RSV disease. Whether RSV vaccination can prevent these complications is an important question in evaluating vaccine efficacy,” the authors wrote. writing.

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