Gamifying daily step goals and financial incentives resulted in increased physical activity over one year. (Circulation)

Heart rate during walking varies widely among healthy middle-aged individuals and cannot be predicted by typical clinical variables. (heart)

In the DEDICATE-DZHK6 population, designed to better reflect routine clinical practice, transcatheter aortic valve replacement had 1-year outcomes consistent with surgery in patients with low or intermediate surgical risk. (New England Medical Journal)

The Arrow QuickFlash radial artery and radial artery/arterial line catheter insertion kit has been declared below class by the FDA due to reports of increased guidewire handle and chamber resistance during use.

About 10% of all deaths after percutaneous coronary intervention could be avoided, according to a study highlighted by the University of Michigan.

Coronary artery bypass graft surgery may be feasibly planned without invasive coronary angiography. (european heart journal)

for research APOC3-Targeted small interfering RNA (siRNA) therapy Prozasilan reduced serum triglycerides in patients with severe hypertriglyceridemia in a phase IIb trial. (JAMA Cardiology)

Initial data supports zerlasiran as an siRNA for lowering lipoprotein(a) levels in people with stable heart disease. (Japan Automobile Manufacturers Association)

Dr. Esperion noted the consistent clinical benefits of bempedoic acid (necretol) across gender, race, and diabetes status in the CLEAR Outcomes trial.

A retrospective study showed that recanalization was still associated with good functional outcome after mechanical thrombectomy in stroke patients in whom no salvageable tissue was identified on CT perfusion imaging. (stroke)

Patients with diabetic cardiomyopathy showed no improvement in exercise performance when taking the highly selective aldose reductase inhibitor AT-001. (Journal of the American College of Cardiology)

Smartphone motion sensors enabled the CardioSignal algorithm to accurately detect stage C heart failure in a prospective, multicenter study. (JACC: Heart failure)

For rural American Indians with limited access to care, telephone-based telehealth services for heart failure with reduced ejection fraction facilitated acceptance of guideline-conforming medical therapy. (JAMA Internal Medicine)

Older people with heart failure and who exhibit hunched breathing, which is shortness of breath after bending forward, had a disproportionately high mortality rate. (European Journal of Preventive Cardiology)

The existing bone drug etidronate slowed the progression of arterial calcification caused by CD73 deficiency, a rare disease. (vascular medicine)

Similar to other racial groups, Asian Americans have shown associations between social determinants of health and cardiovascular disease risk factors. (American Heart Association Journal)