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April 9, 2024
2 minute read
Important points:
- Adults with anxiety or depression are more likely to develop conditions such as high blood pressure that increase the risk of heart disease.
- This association was more pronounced in women younger than 50 years.
ATLANTA — Young women diagnosed with anxiety or depression have a significantly higher risk of developing conditions that increase CVD risk, such as hypertension, hyperlipidemia, and diabetes, researchers report.
The findings were presented at the American College of Cardiology Scientific Sessions.
“Anxiety and depression increase the risk of cardiovascular disease, such as heart attack and stroke, by accelerating the development of cardiovascular disease risk factors such as hypertension, hyperlipidemia, and diabetes.” Dr. Giovanni Sivieri, said Helio, a cardiologist and researcher at Massachusetts General Hospital and Harvard Medical School, and a doctoral student at the University of Padua in Italy. “Among young women, the risk of developing new CV risk factors associated with anxiety and depression is significantly higher than for other age and gender groups. may explain why there is a strong association between anxiety/depression and CVD.
Giovanni Sivieri
Civieri et al. analyzed data from 71,214 adults with no history of CVD at baseline. All were enrolled in the Massachusetts General Brigham Biobank and followed for 10 years. The median age of participants was 50 years, and 55.3% were female. Researchers assessed participants for rates of anxiety and depression, and cardiometabolic conditions, including hypertension, hyperlipidemia, diabetes, and cardiovascular disease.
During follow-up, 38% of participants developed hypertension, hyperlipidemia, or diabetes.
Researchers found that compared to adults without anxiety or depression, adults diagnosed with anxiety or depression were 55% more likely to develop a disease that increases CVD risk (HR = 1.55, 95% CI, 1.47-1.64, 95% CI, 1.47-1.64, P .001). Sensitivity analysis showed that the risk was more pronounced for women compared to men (P .001), and adults under 50 and older adults (P .001).
“In absolute terms, young women were less likely to develop new CV risk factors, but they were most affected by anxiety and depression,” the researchers said in their summary.
In young women, cardiovascular risk factor expression explained 22.1% of the risk of major adverse cardiovascular events associated with anxiety/depression, compared with 17.7% in the overall cohort (P .05).
“While we often feel that young women are a ‘safe group’ when it comes to CVD, our research shows that if young women suffer from depression or anxiety, they may be able to improve their CVD to reduce their risk. “It suggests that we need to screen for risk factors,” Civeri told Healio. “It is unclear whether mental health treatments, such as antidepressants and psychotherapy, help reduce CVD risk. Future research will investigate whether treating anxiety and depression reduces the risk of developing new CV risk factors. , and whether this effect is more pronounced in younger women needs to be investigated.”
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Sivieri G, et al. Summary 1331-218. Presentation location: American College of Cardiology Scientific Sessions. April 6-8, 2024. Atlanta.
Disclosure: Sivieri does not report any relevant financial disclosures.
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