ENew York University Langone heart experts will present their latest clinical findings and research findings at the American College of Cardiology’s (ACC) 2024 Annual Scientific Sessions & Expo, April 6-8 in Atlanta. Masu.

Some of the topics presented include:

• How exposure to air pollution affects heart attack outcomes nationwide
• Whether certain blood markers can help assess risk in patients with chronic coronary artery disease
• Why invasive wire-based tests for diagnosing heart disease affecting the smallest blood vessels in women cannot be replaced by more easily obtained visual estimations
• Perceptions of older adults regarding the use of mobile health applications for cardiac rehabilitation
• Understanding the limitations of relying on heart failure identification from electronic health records

Additionally, Harmony R. Reynolds, M.D., director of the Sarah Ross Souter Center for Women’s Cardiovascular Research at the New York University Grossman School of Medicine, was recognized for her contributions to advancing the understanding of cardiovascular disease with the 2024 Bernadine Healy Award in Women’s CV Disease.・Received the Leadership Award. women’s illness. On April 8, Dr. Reynolds will be formally recognized and honored in her honor at this year’s Convocation Ceremony.

“We are extremely proud of Dr. Reynolds for receiving such a prestigious award, recognizing her significant contributions to the field of women’s cardiology,” said William Goldring Professor of Medicine and Leon Dr. said Glenn I. Fishman, M.D., director of the H.H. Center. Charney Department of Cardiology, New York University Grossman School of Medicine. “The ACC Conference serves as a place for our faculty to explore, learn, and share all of the latest advances in the field. It’s a testament to the efforts of our department.”

At this year’s conference, faculty from the Leon H. Charney Department of Cardiology will participate in more than 70 presentations, on-demand discussions, and poster sessions during the conference. You will also be available for media interviews to discuss the innovative and noteworthy scientific developments that have resulted from the conference. Below are some highlights.

Poster presentation: Association between air pollution and in-hospital myocardial infarction outcomes in a national dataset

Saturday, April 6th, 11:45am

Jonathan Newman, MD, MPH, medical student Luke Bonanni, director of clinical research at New York University’s Langone Heart Center for Cardiovascular Disease Prevention, and their colleagues explore how air pollution affects patients hospitalized with heart attacks across the country. We investigated whether it would have any impact. The research team investigated his two types of pollutants: fine particulate matter and ozone. They found in a large data set that higher exposure to fine particulate matter was associated with a higher likelihood of dying in hospital after a heart attack. However, the association with ozone was not the same.

“This suggests that patients at risk for heart attack should be aware of their local air quality and limit their exposure, especially during periods of poor air quality,” Dr. Newman said. Ta. “You can reduce your exposure by wearing an N95 mask, closing windows and limiting outdoor activities, and using indoor portable air purifiers.”

Poster presentation: Cardiometabolic risk factor burden and circulating biomarkers in patients with chronic coronary artery disease in the ISCHEMIA trial

Sunday, April 7th, 10:15am

Karine Hamo, MD, assistant professor in the Leon H. Charney Department of Cardiology, and colleagues at New York University’s Grossman School of Medicine set out to understand the link between lifestyle and heart disease. The analysis, part of the ISCHEMIA trial, focused on patients with chronic coronary artery disease (CCD) and looked at how their lifestyle and health status affected specific biomarkers in their blood. .

Biomarkers serve as clues to help clinicians understand what’s going on in the body. In this study, Dr. Hamo and his colleagues looked at biomarkers associated with cardiac stretch, injury, inflammation, and platelet activity. By analyzing blood samples from 752 adults, they aimed to understand how cardiometabolic risk factors such as diabetes, hypertension, and obesity affect these biomarkers. The research team found that patients with poorly controlled risk factors had higher levels of biomarkers associated with heart damage and inflammation.

“By understanding these associations, we can better assess a person’s risk for heart disease and adjust treatment accordingly,” Dr. Hamo said. “Interventional studies are needed to determine whether better optimization of comorbidities can reduce cardiac damage and inflammation.”

Poster presentation: Perception of the usefulness of mobile health cardiac rehabilitation in older adults

Sunday, April 7th, 1:15 p.m.

Digital health applications are revolutionizing the way we approach healthcare, but how easy are these mobile applications to use, especially for older adults? Director of the Geriatric Cardiology Program at NYU Langone College John A. Dodson, MD, MPH, medical student Kira Borrello and colleagues set out to answer this question by investigating the perceived usefulness of mobile medical cardiac rehabilitation (mHealth-CR) in older adults. I aimed.

The study was part of the ongoing RESILIENT trial and focused on patients with ischemic heart disease who were 65 years and older. Dr. Dodson and team used the System Usability Scale survey to measure the usability of the mHealth-CR app. The study asks participants to rate various aspects of usability on a scale of 0 to 100, with higher scores indicating better usability. The results showed that older adults found the mHealth-CR app relatively easy to use, with an average score of 68.8 out of 100. However, this study also revealed some differences in ease of use. Older adults who were Hispanic or non-white, and older adults with osteoarthritis were more likely to rate the app as difficult to use.

“While mHealth-CR shows promise as a viable option for cardiac rehabilitation in the elderly population, these findings raise concerns about the accessibility and ease of use of the technology, especially among older adults from diverse backgrounds. “It highlights the importance of addressing disparities,” Dr Dodson said.

Poster presentation: Visual estimation of slow blood flow in coronary arteries is not associated with invasive wire-based diagnosis of coronary microvascular dysfunction

Sunday, April 7th, 2:15 p.m.

When it comes to heart health, understanding the complex mechanics of blood flow within the coronary arteries is critical. Nathaniel R. Smilowitz, MD, Ph.D., assistant professor in the Leon H. Charney Department of Cardiology, and colleagues aimed to investigate the relationship between visual estimation of slow flow in coronary arteries and invasive wire-based diagnosis of coronary microvasculature. A study was conducted on the following. Ischemia and non-obstructed coronary artery (INOCA) dysfunction in patients.

The research team enrolled more than 100 adults with stable ischemic heart disease who underwent invasive coronary angiography, the majority of whom were women. They excluded patients with significant occlusions in major coronary arteries. During the procedure, the angiogram was carefully examined for signs of affecting the smallest blood vessels. In addition, all participants underwent a coronary function test using advanced technology to measure two important indicators of microvascular function: coronary flow reserve (CFR) and index of microcirculatory resistance (IMR). I did.

This study found that visual estimation of slow flow in coronary arteries was not associated with a diagnosis of abnormal CFR, abnormal IMR, or coronary microvascular dysfunction as determined by invasive wire-based testing. This leads to the conclusion that invasive wire-based tests for diagnosing heart diseases affecting the smallest blood vessels in women cannot be replaced by more easily obtained visual estimates.

“This study highlights the importance of leveraging advanced diagnostic tools to improve the care of patients with ischemic heart disease,” Dr. Smilowitz said.

Poster presentation: Getting to the heart of the matter—challenges in diagnosing heart failure from electronic medical records

Sunday, April 7th, 3:15 p.m.

Amrita Mukhopadhyay, MD, Eugene Braunwald, MD, assistant professor of cardiology; Dr. Sharon Klein, internal medicine resident. Researchers investigated why it is difficult for doctors to identify which patients have heart failure from electronic health records (EHRs). The research team found that the difficulties are largely related to two areas. One was the challenge of relying on an incomplete definition of heart failure, which includes vague symptoms and reversible heart conditions. There are also challenges with using EHR data, such as accessing data from other institutions and finding information scattered within the system.

“This highlights the inherent limitations of relying on EHRs to identify heart failure and highlights the need for significant improvements in data collection and quality for quality improvement and research efforts in this area. “We’re emphasizing that,” Dr. Klein said.

Dr. Harmony Reynolds receives Bernadine Healey Leadership Award in Women’s CV Disease

The Bernadine Healey Leadership Award in Women’s CV Disease was established in honor of the accomplishments and memory of Dr. Bernadine Healey, the first woman to head the National Institutes of Health and the first physician to lead the American Red Cross. I did. Dr. Reynolds received this award in recognition of her outstanding contributions to research and care regarding heart disease syndromes that primarily affect women. Her research focuses on understanding the characteristics of heart attacks in women and how best to detect and treat them.

“I am humbled to receive this award named after Dr. Healy, who played such an innovative role in women’s health research and who also happens to be a mentor to my mentor, Dr. Judith S. Hochman. ,” Dr. Reynolds said. “Given the work that ACC has so generously recognized with this award, I would like to thank our patients first and foremost. Share your story and tell us what you need to study and why. Thank you for showing us why it matters. There is so much we can do, and we look forward to continuing to work together to improve women’s lives.”

Media inquiries

katie ulman
Phone: 646-483-3984
Kathryn.Ullman@NYULangone.org