Sedentary time is associated with an increased risk of heart failure (HF) and heart failure with preserved ejection fraction (HFpEF) in older women, according to research published today. JAMA Cardiology.

The 2018 U.S. Physical Activity Guidelines Evidence Report states that 150 minutes of moderate to vigorous physical activity per week reduces the risk of heart failure by 10% compared to no activity. .

To assess whether higher levels of physical activity are associated with a reduced risk of heart failure, data from this study was used as an objective supplement to the Women’s Health Initiative (WHI) Longevity Study conducted in 2016. Obtained from the Physical Activity and Cardiovascular Health (OPACH) study. 2012-2014. A woman (N = 5951) between her 63 and 99 years of age without heart failure wore a triaxial accelerometer on her hip for 7 consecutive days. The risk of heart failure until 2022 was assessed based on physical activity.

The average age of women was 78.6 years, BMI was 28.1, 49.2% were Caucasian, 70.2% did not use a walking aid, 17.8% had no comorbidities, and 51.3% were in good or very good health. I was evaluating myself. And they took her a median of 3133 (IQR, 2303-4547) steps per day.

Overall, 1,488 patients engaged in each of the following minutes of physical activity per day:

• Less than 276
• 276～336
• 337-397
• 397 and above

When stratified by physical activity, the most sedentary participants were older, more likely to be Caucasian, had three or more comorbidities, and reported lower self-esteem than participants who were more active. Fewer people rated their health as “excellent” or “very good” (all participants) P £.002).

Physical activity was positively correlated with physical function and high-density lipoprotein cholesterol levels, and negatively correlated with BMI, blood pressure, glucose, total cholesterol, triglycerides, and C-reactive protein levels (all P <.001).

During follow-up, a total of 407 HF cases, 257 HFpEF, and 110 HF cases with reduced ejection fraction (HFrEF) occurred.

For every 90 minutes of daily physical activity increase, the risk of heart failure (adjusted hazard ratio) [aHR], 0.85; 95% CI, 0.75-0.95) and HFpEF (aHR, 0.78; 95% CI, 0.67-0.91) decreased. No effect on HFrEF was observed.

Similarly, each additional 3600 steps per day was associated with a significantly lower risk of developing HF (aHR, 0.74; 95% CI, 0.63 to 0.88) and HFpEF (aHR, 0.71; 95% CI, 0.57 to 0.88). did. An additional 102 minutes of sedentary time per day significantly increased the risk of heart failure (aHR, 1.17; 95% CI, 1.04-1.33) and HFpEF (aHR, 1.29; 95% CI, 1.10-1.51) did.

Stratifying by physical activity group, we observed a dose-dependent relationship between increased physical activity and decreased HF and HFpEF risk compared to the most sedentary group.

The main limitation of this study is that physical activity data were collected for only 1 week.

The study authors concluded that “…higher than normal levels of optical PA are present.” [physical activity],MVPA [moderate-to-vigorous physical activity], the number of steps per day measured by accelerometers was associated with a lower overall risk of developing HF and HFpEF in women aged 63 to 99 years in a community setting. The longer you are sedentary, the greater the risk. ”

Disclosure: Some study authors declared affiliations with biotechnology, pharmaceutical, and/or device companies. Please see the original bibliography for a complete list of author disclosures.