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March 3, 2024

2 minute read


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Important points:

  • Both STEMI and non-STEMI heart attacks decreased less among men than women from 2011 to 2018.
  • Women underwent revascularization less frequently and were often older with more comorbidities.

Despite significant declines in STEMI and non-STEMI events from 2011 to 2018, women received proportionately fewer revascularization procedures and had higher STEMI mortality rates than men, researchers report did.

Women hospitalized with STEMI or non-STEMI were generally older and had more comorbidities than men, according to findings published in . Circulation: cardiovascular quality and outcomes.



Cardiologist _192016818
Both STEMI and non-STEMI heart attacks decreased less among men than women from 2011 to 2018. Image: Adobe Stock

“Acute myocardial infarction is a major cause of morbidity and mortality in high-income countries. There has been long-standing concern about gender disparities in the treatment and outcomes of acute myocardial infarction for women compared to men. In addition to potentially presenting with different symptoms, women are older than men, experience acute myocardial infarction, and are less likely to undergo coronary revascularization.” Hannah Lu, BSAa resident at the John Seeley School of Medicine at the University of Texas Medical Branch, and colleagues wrote.

Using data from the population-representative International Health Systems Research Collaborative, the researchers determined acute myocardial infarction hospitalization rates, cardiac intervention rates, and We compared the consultation rate and mortality rate. USA, Canada, UK, Netherlands, Israel, Taiwan.

Heart attack incidence in men and women

In all countries, women hospitalized for STEMI or non-STEMI were on average 3 to 4 years older and had higher rates of comorbidities than hospitalized men. However, from 2011 to 2018, at any point in time, she was less than 50% of inpatient women. The only exception was non-STEMI hospitalizations in the United States, which decreased from 50.7% in 2011 to 46.9% in 2018.

In general, the study found that age-standardized rates of STEMI and non-STEMI hospitalizations decreased in all countries for both men and women from 2011 to 2018, but the decline was proportionately smaller for men.

Revascularization and mortality in men and women

Differences in PCI receipt rates for women compared to men varied across countries. However, as of 2018, the frequency of PCI for STEMI was lower among women in all countries, ranging from a 3% decrease in women in the United States to an 8.5% decrease in women in Taiwan.

The proportion of patients undergoing CABG for STEMI decreased in all countries from 2011 to 2018, with fewer women performing it compared to men in all countries except Taiwan. In Taiwan, 3.6% of women with STEMI underwent CABG compared with 3% of men.

The pattern of revascularization for non-STEMI was generally similar in all countries for both 90-day revascularization and revascularization during the index hospitalization.

From 2011 to 2018, 30-day mortality after STEMI increased for both men and women in Canada, the United Kingdom, and Israel, and decreased in the United States, Netherlands, and Taiwan. During this period, non-STEMI mortality increased for both men and women in the UK, but decreased in all other countries except Israel. Mortality increased slightly in Israel and decreased among men.

The 30-day mortality rate after STEMI was higher for women than for men at all times in most countries, ranging from 0.1% higher in the UK to 5.7% higher in Taiwan.

Thirty-day non-STEMI mortality rates were generally lower for women compared to men at any time point in any country.

“From 2011 to 2018, we found that the decline in hospitalizations for acute myocardial infarction was smaller for men than for women in six diverse high-income countries,” the researchers wrote. “We also extend previous research by demonstrating that women are less likely to undergo cardiac intervention and have higher mortality rates after STEMI than men in all countries. In summary, our analysis exemplifies how comparisons of international health systems can be used to better identify patterns of care within and across countries.”

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